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Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptide

IFIH1 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN978410
  • Antigène Tous les produits IFIH1
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-IFIH1 antibody (Catalog #: ARP36486_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    Synonymes
    MDA5 Peptide, Hlcd Peptide, IDDM19 Peptide, MDA-5 Peptide, RLR-2 Peptide, 9130009C22Rik Peptide, Helicard Peptide, RGD1560496 Peptide, interferon induced with helicase C domain 1 Peptide, IFIH1 Peptide, Ifih1 Peptide
    Sujet
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 is a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: Hlcd, IDDM19, MDA-5, MDA5, MGC133047

    Protein Size: 1025
    Poids moléculaire
    117 kDa
    ID gène
    64135
    NCBI Accession
    NM_022168, NP_071451
    UniProt
    Q9BYX4
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