Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Peptide
IGLL1
Reactivité: Humain
Hôte: Synthetic
WB, BP
N° du produit ABIN978447
Aperçu rapide pour Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Peptide (ABIN978447)
Antigène
IGLL1
(Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
Origine
Humain
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-IGLL1 antibody (Catalog #: ARP42547_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) peptide
IGLL1 Reactivité: Souris Hôte: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
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Sujet
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The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 14.1, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, AGM2
Protein Interaction Partner: IGLL1,MYOC
Protein Size: 213 -
Poids moléculaire
- 19 kDa
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ID gène
- 3543
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NCBI Accession
- NM_020070, NP_064455
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UniProt
- P15814
Antigène
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