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Interleukin 2 Receptor, beta (IL2RB) (C-Term) Peptide

IL2RB Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN978506
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour Interleukin 2 Receptor, beta (IL2RB) (C-Term) Peptide (ABIN978506)

Antigène

IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Séquence

    QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-IL2RB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    Sujet

    The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

    Alias Symbols: CD122, P70-75, IL15RB

    Protein Interaction Partner: GNB2L1,IL2,JAK1,CISH,EIF3B,FYN,GNB2L1,GRB2,IL15,IL15RA,IL2,IL2RA,IL2RG,JAK1,JAK3,LCK,LYN,PIK3R1,PTPN6,RAF1,SHB,SHC1,SOCS1,SOCS3,STAT1,STAT3,STAT5A,STAT5B,SYK,CISH,GNB2L1,GRB2,HGS,JAK1,JAK2,SHB,SHC1,SOCS1,STAT1,STAT3,STAT5A,STAT5B,UBC

    Protein Size: 551

    Poids moléculaire

    58 kDa

    ID gène

    3560

    NCBI Accession

    NM_000878, NP_000869

    UniProt

    P14784
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