Interleukin enhancer-binding factor 3 (ILF3) Peptide
ILF3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978525
Aperçu rapide pour Interleukin enhancer-binding factor 3 (ILF3) Peptide (ABIN978525)
Antigène
Interleukin enhancer-binding factor 3 (ILF3)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ILF3 antibody (Catalog #: ARP38969_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Interleukin enhancer-binding factor 3 (ILF3)
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Sujet
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ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: CBTF, DRBF, MMP4, MPP4, NF90, NFAR, NF110, NF90a, NF90b, NFAR2, TCP80, DRBP76, NF110b, NFAR-1, TCP110, MPHOSPH4, NF-AT-90
Protein Interaction Partner: DHX9,EIF2AK2,FUS,GDF9,KRTAP4-12,MAGEA11,MDFI,NDRG1,PLSCR1,PRMT1,SMN2,TRIP6,XPO5,ZNF346,EIF2AK2,FUS,GDF9,HNRNPA1,ILF2,KHDRBS2,KRTAP4-12,MAGEA11,MDFI,MEPCE,PLSCR1,PRKDC,PRMT1,RPAP1,RRP1B,Rrp1b,TRIP6,XPO5
Protein Size: 894 -
Poids moléculaire
- 95 kDa
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ID gène
- 3609
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NCBI Accession
- NM_012218, NP_036350
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UniProt
- Q12906
Antigène
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