Inhibitor of Growth Family, Member 1 (ING1) (N-Term) Peptide
ING1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978546
Aperçu rapide pour Inhibitor of Growth Family, Member 1 (ING1) (N-Term) Peptide (ABIN978546)
Antigène
ING1
(Inhibitor of Growth Family, Member 1 (ING1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- SPAERLVAEA DEGGPSAITG MGLCFRCLLF SFSGRSGVEG GRVDLNVFGS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ING1 Antibody(ARP50511_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
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Sujet
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ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.
Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Protein Interaction Partner: TP53,BRMS1,BRMS1L,C20orf20,DMAP1,EP300,HDAC1,HDAC2,KAT2B,PCNA,RBBP4,RBBP7,RBP1,SAP30,SFN,SIN3A,TP53,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,ACTL6A,ARID1A,C20orf20,CDKN2A,CREBBP,DMAP1,EP300,ESR1,HDAC1,HDAC2,HHT1,HHT2,HIST2H3A,HIST2H3C,HIST4H4,KAT2B,KPNA2,KPNB1
Protein Size: 422 -
Poids moléculaire
- 47 kDa
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ID gène
- 3621
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NCBI Accession
- NM_005537, NP_005528
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UniProt
- Q9UK53
Antigène
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