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Inhibitor of Growth Family, Member 1 (ING1) Peptide

ING1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN978547

Aperçu rapide pour Inhibitor of Growth Family, Member 1 (ING1) Peptide (ABIN978547)

Antigène

ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Origine

Humain

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-ING1 antibody (Catalog #: ARP50512_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    ING1 (Inhibitor of Growth Family, Member 1 (ING1))

    Sujet

    ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

    Protein Interaction Partner: TP53,BRMS1,BRMS1L,C20orf20,DMAP1,EP300,HDAC1,HDAC2,KAT2B,PCNA,RBBP4,RBBP7,RBP1,SAP30,SFN,SIN3A,TP53,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,ACTL6A,ARID1A,CREBBP,DMAP1,EP300,HDAC1,HDAC2,HHT1,HHT2,HIST2H3A,HIST4H4,KAT2B,PCNA,RBBP4,RBBP7,SAP30,SIN3A,SMARCA4,SMARCB1,SMARCC1,SMARCC2,SMARCD1,TP53,TRRAP

    Protein Size: 279

    Poids moléculaire

    32 kDa

    ID gène

    3621

    NCBI Accession

    NM_198219, NP_937862

    UniProt

    Q5T9H0
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