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Integrator Complex Subunit 6 (INTS6) (C-Term) Peptide

INTS6 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN978577

Aperçu rapide pour Integrator Complex Subunit 6 (INTS6) (C-Term) Peptide (ABIN978577)

Antigène

INTS6 (Integrator Complex Subunit 6 (INTS6))

Origine

Humain

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-INTS6 antibody (Catalog #: ARP36404_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    INTS6 (Integrator Complex Subunit 6 (INTS6))

    Sujet

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: DBI-1, DDX26, DDX26A, DICE1, DKFZP434B105, HDB, INT6, Notchl2

    Protein Size: 874

    Poids moléculaire

    99 kDa

    ID gène

    26512

    NCBI Accession

    NM_001039937, NP_001035026

    UniProt

    A8MV98
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