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Iron-Responsive Element Binding Protein 2 (IREB2) Peptide

IREB2 Reactivité: Humain Hôte: Synthetic BP, WB

N° du produit ABIN978591

Aperçu rapide pour Iron-Responsive Element Binding Protein 2 (IREB2) Peptide (ABIN978591)

Antigène

IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Origine

Humain

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Attributs du produit

This is a synthetic peptide designed for use in combination with anti-IREB2 antibody (Catalog #: ARP40509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Iron-Responsive Element Binding Protein 2 (IREB2) peptide
IREB2 Hôte: Synthetic BP, Imm

Iron-Responsive Element Binding Protein 2 (IREB2) peptide
IREB2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC

Iron-Responsive Element Binding Protein 2 (IREB2) (Internal Region) peptide
IREB2 Reactivité: Humain Hôte: Synthetic BP, BI

Indications d'application

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Conseil sur la manipulation

Avoid repeated freeze-thaw cycles.

Stock

-20 °C

Stockage commentaire

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène

IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Sujet

IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD

Protein Interaction Partner: YBX1,YBX1,YBX1

Protein Size: 963

Poids moléculaire

105 kDa

ID gène

3658

NCBI Accession

NM_004136, NP_004127

UniProt

P48200

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