Iron-Responsive Element Binding Protein 2 (IREB2) Peptide
IREB2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978591
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Iron-Responsive Element Binding Protein 2 (IREB2) Peptide (ABIN978591)
Antigène
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-IREB2 antibody (Catalog #: ARP40509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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Sujet
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IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD
Protein Interaction Partner: YBX1,YBX1,YBX1
Protein Size: 963 -
Poids moléculaire
- 105 kDa
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ID gène
- 3658
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NCBI Accession
- NM_004136, NP_004127
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UniProt
- P48200
Antigène
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