Interferon Regulatory Factor 6 (IRF6) Peptide
IRF6
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978612
Aperçu rapide pour Interferon Regulatory Factor 6 (IRF6) Peptide (ABIN978612)
Antigène
IRF6
(Interferon Regulatory Factor 6 (IRF6))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-IRF6 antibody (Catalog #: ARP43608_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Interferon Regulatory Factor 6 (IRF6) peptide
IRF6 Reactivité: Humain, Souris Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IRF6 (Interferon Regulatory Factor 6 (IRF6))
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Sujet
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IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1
Protein Interaction Partner: LBP
Protein Size: 591 -
Poids moléculaire
- 65 kDa
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ID gène
- 3664
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NCBI Accession
- NM_004661, NP_006138
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UniProt
- O14896
Antigène
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