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Interferon Regulatory Factor 8 (IRF8) Peptide

IRF8 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN978615

Aperçu rapide pour Interferon Regulatory Factor 8 (IRF8) Peptide (ABIN978615)

Antigène

IRF8 (Interferon Regulatory Factor 8 (IRF8))

Origine

Humain

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100841_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    IRF8 (Interferon Regulatory Factor 8 (IRF8))

    Sujet

    Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

    Alias Symbols: ICSBP, IRF-8, ICSBP1, H-ICSBP

    Protein Interaction Partner: COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC

    Protein Size: 426

    Poids moléculaire

    48 kDa

    ID gène

    3394

    NCBI Accession

    NM_002163, NP_002154

    UniProt

    Q02556
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