Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide
KEAP1
Reactivité: Humain
Hôte: Synthetic
BP, IHC, WB
-
- Antigène Tous les produits KEAP1
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Origine
- Humain
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-KEAP1 antibody (Catalog #: ARP38981_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Antigène
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Synonymes
- INrf2 Peptide, KLHL19 Peptide, INRF2 Peptide, mKIAA0132 Peptide, Inrf2 Peptide, fb36f11 Peptide, keap1 Peptide, wu:fb36f11 Peptide, KEAP1 Peptide, klhl19 Peptide, zgc:171654 Peptide, kelch like ECH associated protein 1 Peptide, kelch-like ECH-associated protein 1 Peptide, Kelch-like ECH-associated protein 1 Peptide, kelch-like ECH-associated protein 1a Peptide, kelch like ECH associated protein 1 L homeolog Peptide, kelch-like ECH-associated protein 1b Peptide, KEAP1 Peptide, Keap1 Peptide, keap1a Peptide, keap1 Peptide, keap1.L Peptide, keap1b Peptide
- Sujet
-
KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: INrf2, KLHL19
Protein Interaction Partner: BPTF,ETF1,FAM46A,MYO7A,NFE2L2,ARCN1,BBS1,BTRC,C10orf119,COPG,CUL3,ETF1,FAM123B,FAM129B,GABPA,GBAS,GET4,KIAA0564,MAD2L1,MAZ,MYO7A,NFE2L2,OSBPL10,PFAS,PGAM5,RBM45,SASS6,SLK,SQSTM1,TMEM160,TSC22D4,UBC,USP11,ZRANB1
Protein Size: 624 - Poids moléculaire
- 70 kDa
- ID gène
- 9817
- NCBI Accession
- NM_203500, NP_987096
- UniProt
- Q14145
-
Vous êtes ici:
