Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-KRT1 antibody (Catalog #: ARP42278_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
Protein Interaction Partner: CALB2,DSP,EVPL,F12,KNG1,KRT5,MBL2,PRKCE,YWHAQ,CSTA,DSP,FANCA,FANCC,IVL,KNG1,LOR,MBL2,PI3,PRKCE