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Keratin 13 (KRT13) Peptide

KRT13 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN979116

Aperçu rapide pour Keratin 13 (KRT13) Peptide (ABIN979116)

Antigène

Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Origine

Humain

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-KRT13 antibody (Catalog #: ARP42031_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    Sujet

    KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been described.

    Alias Symbols: CK13, K13, MGC161462, MGC3781

    Protein Interaction Partner: KRT7

    Protein Size: 420

    Poids moléculaire

    46 kDa

    ID gène

    3860

    NCBI Accession

    NM_002274, NP_002265

    UniProt

    P13646
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