Leukemia Inhibitory Factor (LIF) Peptide
LIF
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN979312
Aperçu rapide pour Leukemia Inhibitory Factor (LIF) Peptide (ABIN979312)
Antigène
LIF
(Leukemia Inhibitory Factor (LIF))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-LIF antibody (Catalog #: ARP54690_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Leukemia Inhibitory Factor (LIF) peptide (Ovalbumin)
LIF Reactivité: Porc Hôte: Synthetic WB, Imm, SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LIF (Leukemia Inhibitory Factor (LIF))
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Sujet
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LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDF, D-FACTOR, HILDA, DIA
Protein Interaction Partner: IL6ST,LIFR,LIFR
Protein Size: 202 -
Poids moléculaire
- 22 kDa
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ID gène
- 3976
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NCBI Accession
- NM_002309, NP_002300
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UniProt
- P15018
Antigène
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