Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide
LRRC8A
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN979603
Aperçu rapide pour Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide (ABIN979603)
Antigène
LRRC8A
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-LRRC8A antibody (Catalog #: ARP49452_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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Sujet
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LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Alias Symbols: FLJ10337, KIAA1437, LRRC8, AGM5
Protein Size: 810 -
Poids moléculaire
- 94 kDa
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ID gène
- 56262
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NCBI Accession
- NM_019594, NP_062540
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UniProt
- Q8IWT6
Antigène
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