V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide
MAF
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN979702
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide (ABIN979702)
Antigène
MAF
(V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalog #: ARP38607_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Sujet
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: CREBBP,EP300,CREBBP,EP300,ETS1,FOS,JUN,MAF,MAFA,MAFG,MYB,SMARCA5,SOX9,USF2,CREBBP,EP300,ETS1,HOXD12,MAF,MAFG,MYB,SOX9,USF2
Protein Size: 373 -
Poids moléculaire
- 38 kDa
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ID gène
- 4094
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NCBI Accession
- NM_001031804, NP_001026974
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UniProt
- O75444
Antigène
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