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Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (N-Term) Peptide

MAP4K2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN979785
  • Antigène Tous les produits MAP4K2
    MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-MAP4K2 antibody (Catalog #: ARP48632_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
    Synonymes
    BL44 Peptide, GCK Peptide, RAB8IP Peptide, AI385662 Peptide, Rab8ip Peptide, MAP4K2 Peptide, dZ150L22.2 Peptide, map4k2l Peptide, map4k2l-2 Peptide, map4k3l Peptide, si:dz150l22.2 Peptide, si:dz263j20.1 Peptide, zgc:136670 Peptide, mitogen-activated protein kinase kinase kinase kinase 2 Peptide, mitogen activated protein kinase kinase kinase kinase 2 Peptide, MAP4K2 Peptide, Map4k2 Peptide, LOC103346779 Peptide, map4k2 Peptide
    Sujet
    MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

    Alias Symbols: BL44, GCK, RAB8IP

    Protein Interaction Partner: MAP3K1,TRAF2,MAP3K11,RAB8A,TRAF2,MAP2K4,MAP3K1,RAB8A,TRAF2

    Protein Size: 820
    Poids moléculaire
    91 kDa
    ID gène
    5871
    NCBI Accession
    NM_004579, NP_004570
    UniProt
    Q12851
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