N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) Peptide
NECAB3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN980588
Aperçu rapide pour N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) Peptide (ABIN980588)
Antigène
NECAB3
(N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Séquence
- MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NECAB3 Antibody(ARP57669_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
-
Sujet
-
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
Protein Interaction Partner: APBA2,APP,APBA2,IKBKG
Protein Size: 396 -
Poids moléculaire
- 44 kDa
-
ID gène
- 63941
-
NCBI Accession
- NM_031232, NP_112509
-
UniProt
- Q96P71
Antigène
-
Vous êtes ici:
