Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) Peptide
NME1
Reactivité: Humain
Hôte: Synthetic
BP, WB, DB, IHC
N° du produit ABIN980764
Aperçu rapide pour Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) Peptide (ABIN980764)
Antigène
NME1
(Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Dot Blot (DB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NME1 antibody (Catalog #: AVARP00009_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Sujet
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This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: AWD, GAAD, NDPKA, NM23, NM23-H1, NB, NBS, NDKA, NDPK-A
Protein Interaction Partner: HHV4gp086,APEX1,AURKA,GORASP2,ITGB1,KSR1,MIF,NME1,NME3,NME4,POLR1C,PRUNE,RORA,RORB,RRAD,SET,TERF1,TIAM1,WDYHV1,AURKA,GORASP2,ITGB1,NME1,NME3,NME4,POLR1C,PRUNE,RAC1,RORA,RORB,RRAD,SET,TERF1,TIAM1,USP18,WDYHV1
Protein Size: 152 -
Poids moléculaire
- 17 kDa
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ID gène
- 4830
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NCBI Accession
- NM_000269, NP_000260
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UniProt
- P22392
Antigène
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