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Notch 4 (NOTCH4) Peptide

NOTCH4 Hôte: Synthetic BP, WB, IHC
N° du produit ABIN980812
  • Antigène Tous les produits NOTCH4
    NOTCH4 (Notch 4 (NOTCH4))
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-NOTCH4 antibody (Catalog #: ARP32726_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    NOTCH4 (Notch 4 (NOTCH4))
    Synonymes
    INT3 Peptide, NOTCH3 Peptide, Int-3 Peptide, Int3 Peptide, N4 Peptide, Notch4 Peptide, notch 4 Peptide, neurogenic locus notch homolog protein 4 Peptide, NOTCH4 Peptide, Notch4 Peptide, LOC100712850 Peptide
    Sujet
    NOTCH4 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. NOTCH4 is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. NOTCH4 functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. NOTCH4 gene may be associated with susceptibility to schizophrenia in a small portion of cases.

    Alias Symbols: INT3, NOTCH3

    Protein Interaction Partner: DLL4,FBXW7,MAML1,MAML2,MAML3,NOTCH4,PSEN1,PSEN2,RBPJ,SMAD2,SMAD3,SMAD4,MAML1

    Protein Size: 589
    Poids moléculaire
    65 kDa
    ID gène
    4855
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