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NADPH Oxidase 1 (NOX1) Peptide

NOX1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN980821
  • Antigène Tous les produits NOX1
    NOX1 (NADPH Oxidase 1 (NOX1))
    Origine
    Humain
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-NOX1 antibody (Catalog #: ARP46818_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    NOX1 (NADPH Oxidase 1 (NOX1))
    Synonymes
    GP91-2 Peptide, MOX1 Peptide, NOH-1 Peptide, NOH1 Peptide, NOX1a Peptide, NOX1alpha Peptide, Nox-1 Peptide, Nox1 Peptide, NADPH oxidase 1 Peptide, NOX1 Peptide, Nox1 Peptide, nox1 Peptide
    Sujet
    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.

    Alias Symbols: GP91-2, MOX1, NOH-1, NOH1

    Protein Interaction Partner: CYBA,CYBA

    Protein Size: 564
    Poids moléculaire
    65 kDa
    ID gène
    27035
    NCBI Accession
    NM_007052, NP_008983
    UniProt
    Q9Y5S8
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