Oncostatin M Receptor (OSMR) (Middle Region) Peptide
OSMR
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN981219
Aperçu rapide pour Oncostatin M Receptor (OSMR) (Middle Region) Peptide (ABIN981219)
Antigène
Oncostatin M Receptor (OSMR)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-OSMR antibody (Catalog #: ARP46396_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Oncostatin M Receptor (OSMR)
-
Sujet
-
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
Protein Interaction Partner: IL6ST,JAK1,JAK2,OSM,ERBB2,IL6ST
Protein Size: 979 -
Poids moléculaire
- 110 kDa
-
ID gène
- 9180
-
NCBI Accession
- NM_003999, NP_003990
-
UniProt
- Q99650
Antigène
-
Vous êtes ici:
