This is a synthetic peptide designed for use in combination with anti-PARD6A Antibody(ARP42883_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Protein Interaction Partner: PLCB1,PLCB3,CDC42,CDH5,CRB3,ECT2,GLS,MAP2K5,MARK2,MARK4,PARD3,PARD6B,PLCB1,PLCB3,PRKCG,PRKCH,PRKCI,PRKCZ,RAC1,RHOQ,TCP10,TGFBR1,YWHAH,YWHAZ,CDC42,DGKZ,ECT2,MPP5,PARD3,PRKCI,PRKCZ,RAC1,RHOQ