phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide
PDE5A
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN981513
Aperçu rapide pour phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide (ABIN981513)
Antigène
PDE5A
(phosphodiesterase 5A, cGMP-Specific (PDE5A))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Séquence
- TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PDE5A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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Sujet
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This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
Protein Interaction Partner: CASP3,PRKG1
Protein Size: 823 -
Poids moléculaire
- 93 kDa
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ID gène
- 8654
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NCBI Accession
- NM_033437, NP_246273
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UniProt
- O76074
Antigène
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