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Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Peptide

PhC2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN981668
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Peptide (ABIN981668)

Antigène

PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Origine

Humain

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-PHC2 Antibody(ARP51251_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

    Sujet

    In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: EDR2, HPH2, MGC163502, PH2

    Protein Interaction Partner: MAPKAPK3,AFG3L2,BMI1,BSDC1,FHL3,GFI1B,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1,TMEM70,AFG3L2,BMI1,BSDC1,Bmi1,Cbx2,FHL3,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1

    Protein Size: 858

    Poids moléculaire

    91 kDa

    ID gène

    1912

    NCBI Accession

    NM_198040, NP_932157

    UniProt

    Q8IXK0
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