Paired-Like Homeobox 2a (PHOX2A) (N-Term) Peptide
PHOX2A
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits PHOX2A
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PHOX2A antibody (Catalog #: ARP31726_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
- Synonymes
- ARIX Peptide, CFEOM2 Peptide, FEOM2 Peptide, NCAM2 Peptide, PMX2A Peptide, Arix Peptide, Phox2 Peptide, Pmx2 Peptide, Pmx2a Peptide, arix Peptide, sou Peptide, zgc:77364 Peptide, phox2 Peptide, xphox2a Peptide, paired like homeobox 2a Peptide, paired-like homeobox 2a Peptide, paired like homeobox 2a S homeolog Peptide, PHOX2A Peptide, Phox2a Peptide, phox2a Peptide, phox2a.S Peptide
- Sujet
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PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Protein Interaction Partner: ATF6B,CREBBP,HAND2,PHOX2A,PRKACA,CREBBP,HAND2,JUN,PHOX2A
Protein Size: 284 - Poids moléculaire
- 30 kDa
- ID gène
- 401
- NCBI Accession
- NM_005169, NP_005160
- UniProt
- O14813
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