Peptidase Inhibitor 3, Skin-Derived (PI3) (Middle Region) Peptide
PI3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN981720
Aperçu rapide pour Peptidase Inhibitor 3, Skin-Derived (PI3) (Middle Region) Peptide (ABIN981720)
Antigène
PI3
(Peptidase Inhibitor 3, Skin-Derived (PI3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PI3 antibody (Catalog #: ARP45341_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
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Sujet
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PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
Protein Interaction Partner: CELA1,EVPL,CSTA,KRT1,LOR
Protein Size: 117 -
Poids moléculaire
- 6 kDa
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ID gène
- 5266
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NCBI Accession
- NM_002638, NP_002629
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UniProt
- P19957
Antigène
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