PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide
PINX1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN981775
Aperçu rapide pour PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide (ABIN981775)
Antigène
PINX1
(PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PINX1 Antibody(ARP57058_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) peptide
PINX1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Sujet
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PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: MCRS1,MPZ,PAFAH1B2,TERF1,TERT,AHCY,CALM3,CAPRIN1,GTPBP4,HRNR,MCRS1,PABPC1,PABPC4,PAFAH1B2,PLEKHJ1,RPL23A,RPL31,RPS10,RPS16,RPS19,RPS28,RPS3A,TERF1,TERT,TXN
Protein Size: 328 -
Poids moléculaire
- 37 kDa
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ID gène
- 54984
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NCBI Accession
- NM_017884, NP_060354
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UniProt
- Q96BK5
Antigène
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