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Proteolipid Protein 1 (PLP1) (N-Term) Peptide

PLP1 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN981869
  • Antigène Tous les produits PLP1
    PLP1 (Proteolipid Protein 1 (PLP1))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-PLP1 antibody (Catalog #: ARP33843_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    PLP1 (Proteolipid Protein 1 (PLP1))
    Synonymes
    GPM6C Peptide, HLD1 Peptide, MMPL Peptide, PLP Peptide, PLP/DM20 Peptide, PMD Peptide, SPG2 Peptide, Plp Peptide, PLP1 Peptide, plp1 Peptide, DKFZp459O081 Peptide, DKFZp459O113 Peptide, DM20 Peptide, jimpy Peptide, jp Peptide, msd Peptide, rsh Peptide, plp Peptide, hld1 Peptide, mmpl Peptide, plp1a Peptide, pmd Peptide, spg2 Peptide, DMalpha2c Peptide, wu:fc27f01 Peptide, wu:fj36d03 Peptide, wu:fj42d08 Peptide, zgc:110499 Peptide, PLP-B Peptide, plp1-a Peptide, plp1-b Peptide, plp1b Peptide, proteolipid protein 1 Peptide, proteolipid protein (myelin) 1 Peptide, myelin proteolipid protein Peptide, proteolipid protein 1 L homeolog Peptide, proteolipid protein 1a Peptide, proteolipid protein 1 S homeolog Peptide, PLP1 Peptide, Plp1 Peptide, plp1 Peptide, Tsp_11640 Peptide, plp Peptide, plp1.L Peptide, plp1a Peptide, plp1.S Peptide
    Sujet
    PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.

    Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1

    Protein Interaction Partner: CALR,CANX,ITGAV,MAG,MBP,MBP

    Protein Size: 277
    Poids moléculaire
    30 kDa
    ID gène
    5354
    NCBI Accession
    NM_000533, NP_000524
    UniProt
    P60201
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