Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) Peptide
PNKP
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN981900
Aperçu rapide pour Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) Peptide (ABIN981900)
Antigène
PNKP
(Polynucleotide Kinase 3'-Phosphatase (PNKP))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PNKP Antibody(ARP52311_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Sujet
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This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Alias Symbols: PNK, MCSZ, EIEE10
Protein Interaction Partner: XRCC1,KRTAP4-12,MAGEA11,MYOZ1,SMAD5,TRIM37,XRCC1,XRCC4,ATAD3B,DDX20,HEATR2,KRTAP4-12,LAS1L,LIG3,LIG4,MAGEA11,MCM3,MYOZ1,NOL3,NOM1,NUP93,POLB,SLC25A12,TRIM37,XRCC1,XRCC4,YWHAQ
Protein Size: 521 -
Poids moléculaire
- 57 kDa
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ID gène
- 11284
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NCBI Accession
- NM_007254, NP_009185
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UniProt
- Q96T60
Antigène
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