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Podocalyxin-Like (PODXL) Peptide

PODXL Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN981929

Aperçu rapide pour Podocalyxin-Like (PODXL) Peptide (ABIN981929)

Antigène

PODXL (Podocalyxin-Like (PODXL))

Origine

Humain

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-PODXL antibody (Catalog #: ARP44729_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    PODXL (Podocalyxin-Like (PODXL))

    Sujet

    PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of PODXL include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

    Alias Symbols: Gp200, MGC138240, PCLP, PC, PCLP-1

    Protein Interaction Partner: SELL,SLC9A3R2,SELL,SLC9A3R2

    Protein Size: 526

    Poids moléculaire

    53 kDa

    ID gène

    5420

    NCBI Accession

    NM_005397, NP_005388

    UniProt

    Q53ER6
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