POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptide
Aperçu rapide pour POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptide (ABIN982009)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-POU3F3 antibody (Catalog #: ARP33062_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POU3F3 (POU Class 3 Homeobox 3 (POU3F3))
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Sujet
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POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Alias Symbols: BRN1, OTF8
Protein Interaction Partner: POU3F4,PPP1R15A,SOX10,SOX11,SOX8,POU3F4
Protein Size: 500 -
Poids moléculaire
- 50 kDa
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ID gène
- 5455
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NCBI Accession
- NM_006236, NP_006227
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UniProt
- P20264
Antigène
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