This is a synthetic peptide designed for use in combination with anti-PPP1R8 antibody (Catalog #: ARP40411_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
Protein Interaction Partner: C14orf1,C7orf64,CDC5L,CRMP1,CSNK2A1,CSNK2A2,EED,GBP2,HDAC2,LYN,MELK,PPP1CA,PPP1CC,PRKACA,SETDB1,SF3B1,STC2,C14orf1,C7orf64,CRMP1,EED,GBP2,HDAC2,LYN,NME2,PPP1CA,PPP1CB,PPP1CC,PRKACA,SETDB1,SF3B1,STC2