PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) Peptide
PRDM1
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN982162
Aperçu rapide pour PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) Peptide (ABIN982162)
Antigène
PRDM1
(PR Domain Containing 1, with ZNF Domain (PRDM1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PRDM1 antibody (Catalog #: P100596_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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Sujet
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PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Alias Symbols: BLIMP1, MGC118922, MGC118923, MGC118924, MGC118925, PRDI-BF1
Protein Interaction Partner: AES,ATXN1,IRF4,TLE1,TLE2,EHMT2,HDAC1,HDAC2,HIST2H3A,KDM1A,PRMT5,PRMT7,SUV39H1,TLE1,TLE2
Protein Size: 691 -
Poids moléculaire
- 77 kDa
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ID gène
- 639
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NCBI Accession
- NM_182907, NP_878911
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UniProt
- Q86WM7
Antigène
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