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Paired Related Homeobox 2 (PRRX2) (N-Term) Peptide

PRRX2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN982297

Aperçu rapide pour Paired Related Homeobox 2 (PRRX2) (N-Term) Peptide (ABIN982297)

Antigène

PRRX2 (Paired Related Homeobox 2 (PRRX2))

Origine

Humain

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-PRRX2 antibody (Catalog #: ARP39248_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    PRRX2 (Paired Related Homeobox 2 (PRRX2))

    Sujet

    PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

    Alias Symbols: MGC19843, PMX2, PRX2

    Protein Interaction Partner: SOX10

    Protein Size: 253

    Poids moléculaire

    27 kDa

    ID gène

    51450

    NCBI Accession

    NM_016307, NP_057391

    UniProt

    Q99811
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