Regulator of Calcineurin 1 (RCAN1) (Middle Region) Peptide
RCAN1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN982785
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Regulator of Calcineurin 1 (RCAN1) (Middle Region) Peptide (ABIN982785)
Antigène
RCAN1
(Regulator of Calcineurin 1 (RCAN1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RCAN1 antibody (Catalog #: ARP38457_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Sujet
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: GSK3B,MAP3K3,MAPK3,PPP3CA,UXT,PPP3CA,UBC
Protein Size: 252 -
Poids moléculaire
- 28 kDa
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ID gène
- 1827
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NCBI Accession
- NM_004414, NP_004405
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UniProt
- P53805
Antigène
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