Replication Factor C (Activator 1) 3, 38kDa (RFC3) Peptide
RFC3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN982866
Aperçu rapide pour Replication Factor C (Activator 1) 3, 38kDa (RFC3) Peptide (ABIN982866)
Antigène
RFC3
(Replication Factor C (Activator 1) 3, 38kDa (RFC3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RFC3 antibody (Catalog #: ARP46084_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
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Sujet
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: MGC5276, RFC38
Protein Interaction Partner: PCNA,CHTF8,PCNA,RFC1,RFC4,BRD4,CHTF18,MEPCE,PCNA,RAD17,RFC1,RFC4,USP20
Protein Size: 356 -
Poids moléculaire
- 40 kDa
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ID gène
- 5983
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NCBI Accession
- NM_002915, NP_002906
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UniProt
- P40938
Antigène
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