Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptide
RIPK3
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN983003
Aperçu rapide pour Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptide (ABIN983003)
Antigène
RIPK3
(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RIPK3 antibody (Catalog #: ARP31513_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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Sujet
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RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Alias Symbols: RIP3, RIP3 beta, RIP3 gamma
Protein Interaction Partner: RIPK1,TICAM1,TNFRSF1A,TRAF2,RIPK1,TICAM1,TNFRSF1A,TRAF2
Protein Size: 518 -
Poids moléculaire
- 57 kDa
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ID gène
- 11035
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NCBI Accession
- NM_006871, NP_006862
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UniProt
- Q9Y572
Antigène
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