Ring Finger Protein 19A (RNF19A) (N-Term) Peptide
RNF19A
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RNF19A
- RNF19A (Ring Finger Protein 19A (RNF19A))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RNF19A antibody (Catalog #: ARP43197_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RNF19A (Ring Finger Protein 19A (RNF19A))
- Synonymes
- RNF19 Peptide, RNF19A Peptide, AA032313 Peptide, Dorfin Peptide, Rnf19 Peptide, UIP117 Peptide, Ubce7ip2 Peptide, XYbp Peptide, ring finger protein 19A, RBR E3 ubiquitin protein ligase Peptide, ring finger protein 19A Peptide, RNF19A Peptide, Rnf19a Peptide
- Sujet
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RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: DKFZp566B1346, DORFIN, RNF19
Protein Interaction Partner: CASR,SNCAIP,SOD1,SUFU,TUBG1,TUBG2,UBE2E2,UBE2L3,UBE2L6,VCP,SOD1,UBE2L3,UBE2L6
Protein Size: 838 - Poids moléculaire
- 91 kDa
- ID gène
- 25897
- NCBI Accession
- NM_015435, NP_056250
- UniProt
- Q9NV58
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