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RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3) (Middle Region) Peptide

RNPC3 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN983111
  • Antigène Tous les produits RNP (RNPC3)
    RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-RNPC3 antibody (Catalog #: ARP40868_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
    Synonymes
    rnp Peptide, rbm40 Peptide, zgc:136847 Peptide, RBM40 Peptide, RNP Peptide, SNRNP65 Peptide, 2810441O16Rik Peptide, AI447568 Peptide, C030014B17Rik Peptide, RNA binding region (RNP1, RRM) containing 3 Peptide, RNA-binding region (RNP1, RRM) containing 3 Peptide, RNPC3 Peptide, rnpc3 Peptide, Rnpc3 Peptide
    Sujet
    RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.

    Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP

    Protein Interaction Partner: RNU11,RNU12-2P

    Protein Size: 517
    Poids moléculaire
    58 kDa
    ID gène
    55599
    NCBI Accession
    NM_017619, NP_060089
    UniProt
    Q96LT9
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