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Runt-Related Transcription Factor 2 (RUNX2) Peptide

RUNX2 Hôte: Synthetic BP, WB
N° du produit ABIN983331
  • Antigène Tous les produits RUNX2
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-RUNX2 antibody (Catalog #: ARP36679_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Synonymes
    AML3 Peptide, CBF-alpha-1 Peptide, CBFA1 Peptide, CCD Peptide, CCD1 Peptide, CLCD Peptide, OSF-2 Peptide, OSF2 Peptide, PEA2aA Peptide, PEBP2aA Peptide, Cbf Peptide, Cbfa-1 Peptide, Cbfa1 Peptide, LS3 Peptide, Osf2 Peptide, Pebp2a1 Peptide, Pebpa2a Peptide, runx2 Peptide, RUNX2 Peptide, ccd Peptide, aml3 Peptide, ccd1 Peptide, osf2 Peptide, cbfa1 Peptide, pea2aa Peptide, pebp2a1 Peptide, pebp2a2 Peptide, pebp2aa Peptide, pebp2aa1 Peptide, runt related transcription factor 2 Peptide, runt-related transcription factor 2a Peptide, runt-related transcription factor 2 Peptide, runt related transcription factor 2 L homeolog Peptide, RUNX2 Peptide, runx2a Peptide, Runx2 Peptide, runx2 Peptide, LOC703331 Peptide, LOC100549663 Peptide, runx2.L Peptide
    Sujet
    The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

    Protein Interaction Partner: RB1,AR,AXIN1,CBFB,CCNB1,CDK1,CEBPB,DVL2,EP300,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MAP3K4,MSX2,MYST4,PRKCD,RB1,SMAD2,SMAD3,SMAD6,TAF1A,UBTF,XRCC5,XRCC6,YAP1,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MSX2,MYST4,SMAD1,SMAD2,SMAD3,SMAD5,STUB1,THOC4,TLE1,YAP1

    Protein Size: 589
    Poids moléculaire
    64 kDa
    ID gène
    860
    UniProt
    Q5T802
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