Retinoid X Receptor, gamma (RXRG) Peptide
Aperçu rapide pour Retinoid X Receptor, gamma (RXRG) Peptide (ABIN983357)
Antigène
Origine
Source
Application
-
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RXRG antibody (Catalog #: ARP38881_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
-
Sujet
-
RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NR2B3, RXRC
Protein Interaction Partner: CAMK2B,CHGB,CREBBP,LRSAM1,MAP4,NCOA6,NCOR2,NR1H2,NR1H3,NR1H4,NR1I2,NR4A1,PNO1,PPARA,PPARD,PPARG,RARA,RARB,RARG,SRF,THRA,THRB,VDR,ITGB3BP,JUB,NR0B2,NR4A1,Nr0b2,PPARA,RARA,RPAP2,SRF
Protein Size: 463 -
Poids moléculaire
- 51 kDa
-
ID gène
- 6258
-
NCBI Accession
- NM_006917, NP_008848
-
UniProt
- P48443
Antigène
-