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Sterol Carrier Protein 2 (SCP2) (Middle Region) Peptide

SCP2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN983465

Aperçu rapide pour Sterol Carrier Protein 2 (SCP2) (Middle Region) Peptide (ABIN983465)

Antigène

SCP2 (Sterol Carrier Protein 2 (SCP2))

Origine

Humain

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-SCP2 antibody (Catalog #: ARP56538_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    SCP2 (Sterol Carrier Protein 2 (SCP2))

    Sujet

    SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

    Alias Symbols: DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI

    Protein Interaction Partner: ACAA2,ACOX1,CAV1,EHHADH,CAV1,PITPNA

    Protein Size: 322

    Poids moléculaire

    35 kDa

    ID gène

    6342

    NCBI Accession

    NM_001007098, NP_001007099

    UniProt

    Q6NXF4
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