SEC63 Homolog (SEC63) Peptide
SEC63
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits SEC63
- SEC63 (SEC63 Homolog (SEC63))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SEC63 antibody (Catalog #: ARP46839_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SEC63 (SEC63 Homolog (SEC63))
- Synonymes
- DNAJC23 Peptide, ERdj2 Peptide, PRO2507 Peptide, SEC63L Peptide, 5730478J10Rik Peptide, AI649014 Peptide, AW319215 Peptide, SEC63-like Peptide, zgc:92718 Peptide, SEC63 homolog, protein translocation regulator Peptide, SEC63-like (S. cerevisiae) Peptide, SEC63 homolog, protein translocation regulator L homeolog Peptide, SEC63 Peptide, Sec63 Peptide, sec63 Peptide, sec63.L Peptide
- Sujet
-
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: SEC61B,SEC62,GSTK1
Protein Size: 760 - Poids moléculaire
- 88 kDa
- ID gène
- 11231
- NCBI Accession
- NM_007214, NP_009145
- UniProt
- Q9UGP8
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