Splicing Factor 1 (SF1) Peptide
SF1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN983614
Aperçu rapide pour Splicing Factor 1 (SF1) Peptide (ABIN983614)
Antigène
Splicing Factor 1 (SF1)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SF1 antibody (Catalog #: ARP41213_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Splicing Factor 1 (SF1)
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Sujet
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SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: D11S636, ZFM1, ZNF162, BBP, MBBP
Protein Interaction Partner: BCL2,DDX17,EWSR1,FUS,PLSCR1,PRKG1,PRPF40A,RBPMS,TAF15,TCERG1,TRIM23,U2AF2,WWP2,DDX17,EWSR1,FUS,PLSCR1,RBPMS,TAF15,TCERG1,TRIM23,U2AF2,U2AF2,WWP2
Protein Size: 638 -
Poids moléculaire
- 69 kDa
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ID gène
- 7536
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NCBI Accession
- NM_201995, NP_973724
Antigène
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