Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (Middle Region) Peptide
SIGLEC7
Reactivité: Humain
Hôte: Synthetic
WB, BP
N° du produit ABIN983742
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (Middle Region) Peptide (ABIN983742)
Antigène
SIGLEC7
(Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
Origine
Humain
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SIGLEC7 antibody (Catalog #: ARP47017_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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Sujet
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SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response, it may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC7 mediates inhibition of natural killer cells cytotoxicity. It may also play a role in hemopoiesis. SIGLEC7 inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Alias Symbols: AIRM1, CDw328, D-siglec, QA79, SIGLEC-7, p75, p75/AIRM1, CD328
Protein Interaction Partner: GRB2,PTPN11,TRAF4
Protein Size: 467 -
Poids moléculaire
- 51 kDa
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ID gène
- 27036
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NCBI Accession
- NM_014385, NP_055200
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UniProt
- Q9Y286
Antigène
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