Premelanosome Protein (PMEL) Peptide
PMEL
Reactivité: Humain
Hôte: Synthetic
BP, IHC, WB
N° du produit ABIN983749
Aperçu rapide pour Premelanosome Protein (PMEL) Peptide (ABIN983749)
Antigène
Melanoma gp100 (PMEL)
(Premelanosome Protein (PMEL))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SILV antibody (Catalog #: ARP46802_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Sujet
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SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
Protein Size: 661 -
Poids moléculaire
- 70 kDa
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ID gène
- 6490
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NCBI Accession
- NM_006928, NP_008859
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UniProt
- P40967
Antigène
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