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Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide

SNRPB Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN984197

Aperçu rapide pour Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide (ABIN984197)

Antigène

SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-SNRPB antibody (Catalog #: ARP40443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

    Sujet

    SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

    Alias Symbols: COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'

    Protein Interaction Partner: GEMIN6,RBBP6,SMN1,ASCC2,C14orf1,CD2BP2,CLNS1A,COIL,CTDP1,DDX20,DHX9,GEMIN4,GEMIN5,GEMIN6,GEMIN7,GIGYF2,LSM11,PRMT5,PSMA3,SKIV2L,SMN2,SMN2,SMNDC1,SNRPB,SNRPD1,SNRPD3,STRAP,STXBP2,STXBP3,TOP3B,WBP4,WDR77,AIRE,ASCC2,C14orf1,CLNS1A,COIL,DDX20,DYNC1H1,EFTUD2,FNBP4,GEMIN4,GEMIN6,GEMIN7,HTATSF1,KHK,LGALS1,MEPCE,PRPF8,PSMA3,SART3,SF3A2,SMN1,SMN2,SNRNP200,SNRPD3,SNUPN,TOP3B,WBP4,WDR77

    Protein Size: 231

    Poids moléculaire

    24 kDa

    ID gène

    6628

    NCBI Accession

    NM_003091, NP_003082

    UniProt

    Q66K91
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