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Snurportin 1 (SNUPN) (Middle Region) Peptide

SNUPN Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN984212
  • Antigène Tous les produits Snurportin 1 (SNUPN)
    Snurportin 1 (SNUPN)
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-SNUPN antibody (Catalog #: ARP40598_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Snurportin 1 (SNUPN)
    Synonymes
    rnut1 Peptide, zgc:77819 Peptide, wu:fc41a03 Peptide, SNUPN Peptide, kpnbl Peptide, snurportin1 Peptide, KPNBL Peptide, RNUT1 Peptide, Snurportin1 Peptide, 0610031A09Rik Peptide, Rnut1 Peptide, Snupn1 Peptide, snurportin 1 Peptide, snupn Peptide, SNUPN Peptide, Snupn Peptide
    Sujet
    The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

    Alias Symbols: KPNBL, RNUT1, Snurportin1

    Protein Interaction Partner: ENO2,KPNB1,PAFAH1B2,PEX5,RPL17,TNNT3,XPO1,DDX20,ENO2,KPNB1,PEX5,RAN,SMN1,SNRPB,TNNT3,XPO1,ZNF259

    Protein Size: 360
    Poids moléculaire
    41 kDa
    ID gène
    10073
    NCBI Accession
    NM_005701, NP_005692
    UniProt
    O95149
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